List of Information Sheets for Master’s Study Programme in Biotechnology

Compulsory subjects
1.	Agricultural Biotechnologies
2.	Bachelor Thesis Defence
3.	Bioanalytical Chemistry
4.	Bioengineering
5.	Biofuels and Products from Renewable Resources
6.	Biotechnologies II (state examination)
7.	Environmental Biotechnologies 
8.	Pharmaceutical and Medical Biotechnologies
9.	Genomics 
10.	Industrial Biotechnologies
11.	Instrumental Methods of Analysis 
12.	Laboratory Practice for Term Paper I
13.	Laboratory Practice for Term Paper II
14.	Laboratory Practice for Term Paper III
15.	Laboratory Practice for Master Thesis
16.	Laboratory Practice in Biotechnologies I
17.	Laboratory Practice in Biotechnologies II
18.	Laboratory Practice in Biotechnologies III
19.	Master Thesis Seminar
20.	Molecular Biology II
21.	Proteomics
22.	Application of Recombinant DNA Techniques

Compulsory Elective subjects
1.	Advanced Analytical and Bioanalytical Methods (state examination)
2.	Applied Microbiology
3.	Biochemistry II
4.	Bioorganic Chemistry
5.	Computer-Aided Molecular Design
6.	Environmental Chemistry
7.	Food Safety
8.	Forensic Molecular Biology and Chemistry 
9.	Chemometrics 
10.	Methods of Biomacromolecular Analysis
11.	Molecular Biological Analysis of Genomes and Proteomes (state examination)
12.	Molecular Biology Databases
13.	Specific Cloning Systems

Selective subjects
1.	Biotechnological Applications of Bacteriophages and Viruses
2.	Catalysis and Biocatalysis 
3.	Genetically Modified Organisms 
4.	Legislation and Biological Safety of Biotechnologies
5.	Natural Substances and Synthesis of Pharmaceuticals
6.	Scientific Research Design
Compulsory Subjects

University 
University of Ss. Cyril and Methodius in Trnava
Fakulty
Faculty of Natural sciences 
Course unit tytle
Computer modeling of molecules
Course unit code
KBT/md317
Type 
Training course using the computer 
Cycle
I. cycle, Bc.
Year of study 
II. year
Semester/trimester 
Winter 
Number of ECTS credits allocated
3
Learning outcomes
The goal of the course is to study modern methods and principles used in the design, research and development of new drugs within the newly constituted rational design of molecules. Course includes applications in biology, pharmacology, medicine. Graduation of the course brings the student knowledge of molecular modeling methods and their application to solve problems in chemistry, biochemistry and biology.
Mode of delivery 
 Work with students using computer equipment 
Prerequisites and co-requisites
Chemistry, Basic biochemistry 
Course content
Bringing students new knowledge in the field of molecular bases in development of new materials and drugs by using modern methods of computer aided design of molecules (CAMD) and drugs (CADD). Use of computer graphics to display and manipulate chemical structures for synthesis of new molecules "in silico, for determination their conformation and calculating their physico-chemical properties. Methods of molecular mechanics, semi-empirical, quantum-mechanical calculations and methods of molecular dynamics will be used. Simulated will be two cases, known receptor obtained from the Protein Data Bank - "docking" inhibitors of the catalytic site of the enzyme (receptor) and the case where the receptor is not known - applied will be the method of active analogs. Training course will be finished by QSAR study of computed parameters toward the experimental physical and biological parameters in linear and logarithmic form.
Recommended or required reading 
Remko, M.: Základy medicínskej a farmaceutickej chémie. Bratislava, SAP, 392 s., 2005. ISBN 80-89104-64-9 
Planned learning activities and teaching methods
Computer work under the guidance of teacher + individual work using the computer technology
Assessment methods and criteria
Continuous evaluation: Elaboration of the setting every week at a seminar, Final evaluation: Elaboration of the final setting
Language of instruction
English
Name of lecturer(s)
Ing. Tibor Maliar, PhD. 
Supervisor
Prof. RNDr. Ján Kraic, PhD.  
Last modification
13/01/2017